Dr Paul Thompson is developing advanced cell culture techniques to study Vitamin D function and metabolism using specialised labs at C-TRIC, Derry’s award winning research centre.
Paul, a lecturer in molecular biology at the University of Ulster, is investigating how Vitamin D influences the absorption of pharmaceutical drugs via the gut, utilising live clinical tissue.
In order to explore this, he is employing a range of cutting edge techniques on living clinical tissue including ex vivo tissue culture coupled with gene expression analysis.
Paul says: “Our work examines how Vitamin D functions at a molecular level and it is imperative that we extend our knowledge in a clinical context through collaboration with clinicians and access to viable clinical tissue. It would be extremely difficult to undertake this type of research without a facility like C-TRIC.”
The research is being undertaken in collaboration with Dr William Dickey, Consultant Gastroenterologist at the Westeran Health Trust.