Between September 3 and September 9, there were 1,091 cases giving a seven day rate of 721.2 per 100,000, down from 724.5 on Thursday.
Only Fermanagh/Omagh has a higher rate at 749.6.
Western Trust relaxes COVID-19 visiting restrictions - next review September 5
21 pictures of ‘Inspirational’ Niall’s Walk for Duchenne in Derry
Mother of young gay girl hails LGBTQ+ board in Western Trust children's ward
Boy rescued over 150m from shore by off-duty lifeguard in County Derry
Derry community secures new defibrillator at busy carriageway
Ards and North Down (377.8), Antrim and Newtownabbey (448.8), Newry, Mourne and Down (491.8), Belfast (492.8), Causeway Coast and Glens (513), Mid and East Antrim (525.6), Mid Ulster (532.6), Lisburn and Castlereagh (598.7), Armagh City, Banbridge and Craigavon (655.4) all have lower rates than Derry/Strabane.
The average rate for the north is 553.2.
The daily change in the cumulative number of patients with a positive test in Derry and Strabane between September 8 and September 9 was 162.
In total 23,289 people have now tested positive for the illness in Derry and Strabane.
A breakdown of the number of vaccinations by postcode shows that 80,735 have been administered in BT48 and 82,348 have been administered in BT47 - 163,083 in total in Derry.