The Glenshane Pass has re-opened after heavy snowfall forced authorities to close the road earlier on Saturday.
Motorists should exercise care when driving said the PSNI.
The 212 Derry to Belfast bus service is now operating again however, Translink said some delays are expected.
Heavy snowfall overnight rendered the main route between Derry and Belfast impassable to motorists.
The Met Office have issued a yellow weather warning for Derry and other parts of the North. The warning is for both Saturday and Sunday.
The yellow weather warning urges people to be aware of possible snow, ice and rain that could lead to dangerous driving conditions.
It took local community worker Jeanette Warke and a group of parents from the Fountain Estate more than four and a half hours to reach Belfast this morning. The journey usually takes an hour and 40 minutes.