Between August 4 and August 10, there were 945 cases giving a seven day rate of 624.7 per 100,000, up from 615.4 on Tuesday.
Only Fermanagh and Omagh (631.2) is recording a higher rate than Derry/ Strabane.
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Mid and East Antrim (352.5), Ards and North Down (378.4), Lisburn and Castlereagh (405.5), Antrim and Newtownabbey (411.1), Armagh City, Banbridge and Craigavon (414.9), Newry, Mourne and Down (416.8), Causeway Coast and Glens (461.9), Belfast (522.8) and Mid Ulster (607.3) all have lower rates than Derry/Strabane.
The average rate for the north is 487.4.
The daily change in the cumulative number of patients with a positive test in Derry and Strabane between August 9 and August 10 was 143.
In total 18,149 people have now tested positive for the illness in Derry and Strabane.
A breakdown of the number of vaccinations by postcode shows that 75,454 have been administered in BT48 and 78,017 have been administered in BT47 - 153,471 in total in Derry